scanning electron micrograph of electrospun material

Advantages of electrospinning

Advantages of electrospinning

Guiding the body to heal itself

Electrospun biomaterials integrate with the body and accelerate healing.

Electrospun biomaterials are particularly useful in implantable medical products because their fibrous architecture mimics the native extracellular matrix of human tissue. When this architecture is carefully engineered, electrospun biomaterials promote new tissue ingrowth and revitalization of damaged tissue, thereby accelerating healing. Moreover,  electrospun biomaterials typically avoid an adverse fibrotic response and resulting scar tissue formation inside the patient endemic to traditional materials.

A super zoomed in microfiber shard
A super zoomed in microfiber shard
Enhanced biocompatibility

Promoting tissue restoration while avoiding fibrosis

Decades of research has shown that electrospun biomaterials stimulate tissue restoration and robust neovascularization due to their porous fibrous network, resembling the structure of the body’s own extracellular matrix. Thanks to this biomimetic architecture and pro-healing environment, research indicates the fibrotic response to implanted electrospun biomaterials can be significantly reduced. Because implant-related fibrosis continues to hinder the long-term performance of numerous medical implants, electrospun biomaterials can provide new avenues to improve biocompatibility and functionality of medical devices.

fibrotic response figure
Restorative bioinstructive scaffolds

Ideal microenvironments for tissue healing

VIVOLTA’s electrospun biomaterials can be engineered to serve as bioinstructive scaffolds – designed to safely resorb over time or last a lifetime.

VIVOLTA has deep experience electrospinning both non-resorbable and resorbable medical grade polymers. Using resorbable polymers, VIVOLTA can design electrospun medical implants to be partially or fully resorbed by the body in a safe manner. Electrospun medical implants can be engineered to resorb at a similar rate to the formation of newly restored tissue grown throughout the implant, then safely disappear as the body gradually absorbs the implant.

resorption graphic
The medispin advantage

Medical electrospinning is now scalable

Despite the clear utility of medical electrospinning, the major drawback of this technology has historically been lack of consistency, lack of scalability, high scrap-rates, and prohibitively high costs.

VIVOLTA has solved these problems with the invention of the MediSpinTM platform – the world’s first and only fully automated, high-throughput medical electrospinning production system – delivering electrospun medical products at the consistency, scale, and price point required by the medical industry.

GBO IME_MedispinXL
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Biochemical illustration.

Versatility of electrospinning

Medical electrospinning is a versatile manufacturing process capable of achieving a wide range of design requirements.

Our solutions

How can VIVOLTA support your development or manufacturing project with best-in-class medical electrospinning services?