The Electrospinning Machine Built for Reproducible Research

The What Is Electrospinning page explains the process and science — the Taylor cone, jet behavior, and how each parameter influences fiber formation. This page is commercial and application-specific: it maps the design goals and process challenges of each field to the exact EC-CLI machine capabilities and add-on modules that solve them, so you can specify the right system.

Throughput scales through equipment rather than a new machine: the EM-MN4 multi-nozzle multiplies deposition up to 4×, and adding an EM-TNS translation nozzle stage to an EM-RDC or EM-RTC collector runs a second nozzle simultaneously. For true clinical or commercial volume, processes developed on the EC-CLI transfer to VIVOLTA’s automated MediSpin™ platform in our ISO 13485 facility.

Independent closed-loop control of temperature (20–45 °C, ±0.5 °C) and humidity (10–80% RH, ±2%) is standard on every EC-CLI, continuously verifying actual conditions against your setpoints even during multi-hour runs. Because relative humidity strongly governs fiber diameter and surface morphology, controlling it is what makes the media you validate the media you can reproduce — regardless of the ambient lab climate or the day.

Core–shell (coaxial) fibers require the EM-CAX coaxial nozzle — 0.4 mm core, 1.2 mm shell, custom sizes on request — and typically two independent EP-HRU syringe pumps so the core and shell feeds are controlled separately. Pair the EM-CAX with the EM-GSM gas shield when the shell uses a volatile solvent, and the EM-LTE low-temperature collector when you also need very high porosity.

Yes. The EM-TMM thickness measurement module monitors layer build-up in real time (variation typically 5σ < 50 µm) so separator and gas-diffusion-layer thickness stays within spec, while the EM-RDC gives large, orientation-controlled membranes and dual-polarity voltage stabilizes the thicker mats robust separators require. Integrated climate control keeps the precursor mat identical run to run before any carbonization step.

For air or liquid filtration media, start with the EC-CLI base machine for climate-controlled, reproducible fiber diameter, then add the EM-RDC rotating drum for large uniform membranes and the EM-MN4 multi-nozzle to reach usable media area. Add the EM-GSM gas shield if you spin volatile solvent systems such as PVDF in DMF, the EM-TMM for in-line areal-thickness QC, and the EM-ASM anti-statics module for thicker depth filters.

Yes. VIVOLTA supports laboratories worldwide, including across North America, with specialist input available remotely and on-site, coordinated through our US commercial office in Dallas, Texas, and our European headquarters.

Yes. The EC-CLI shares core technology with the MediSpin™ production platform, so a process proven on your machine can be transferred and validated at manufacturing scale through VIVOLTA’s CDMO — your parameters carry over.

Custom process development is run on your EC-CLI for your application. Depending on the engagement, work can be carried out with your team on your machine and supported remotely by our specialists; specifics are scoped during the application assessment.

Custom process development supports owners of an EC-CLI electrospinning machine — our scientists help you develop and document a reproducible protocol that your own team then runs. CDMO services are different: there, VIVOLTA develops and manufactures the process for you in our ISO 13485-certified facility. Many customers start with machine-level support and scale to the CDMO later.

Service is performed by VIVOLTA’s own technical team — the specialists who design and build the EC-CLI — rather than a third-party intermediary.

Packages typically include scheduled preventive servicing, on-site and remote diagnostics, priority access to genuine spare parts and consumables, and validation of climate-control accuracy. Scope is matched to your system configuration and usage. All VIVOLTA equipment carries a 2-year standard warranty, with extended packages available.

Training covers all aspects of the EC-CLI, from basic operation to advanced features — climate-control set-up, nozzle and collector configuration, high-voltage and voltage-ramp operation, automation and data logging, and routine maintenance. Sessions are tailored to your applications so that your team can operate and maintain the system independently.

Yes. VIVOLTA provides on-site service and maintenance across North America, supported by our US commercial office in Dallas, Texas, alongside global coverage from our European headquarters. A 480 VAC 3-phase power-converter kit is available for US installations.

Yes. VIVOLTA offers comprehensive on-site installation, user training programs, and ongoing technical support worldwide — including the US (Dallas, TX), Japan, and Australia. Our team provides guidance on system configuration, module selection, and process development. Custom process-development support is available from VIVOLTA’s in-house scientists, and extended service and maintenance packages keep your electrospinning equipment running at peak performance.

Several equipment strategies help. The EM-MN4 multi-nozzle uses four parallel nozzles to multiply fiber deposition. Adding an EM-TNS translation nozzle stage to the EM-RDC or EM-RTC collector enables a second nozzle to operate simultaneously, doubling throughput. Linking multiple EP-HRU syringe pumps gives synchronous flow control for multi-channel setups. All of these can be combined in a single session for maximum throughput.

Coaxial electrospinning produces core–shell nanofibers where the core and shell are different materials — enabling drug encapsulation, fiber reinforcement, and surface functionalization. You’ll need the EM-CAX coaxial nozzle (0.4 mm core, 1.2 mm shell — custom sizes on request) and typically two independent EP-HRU syringe pumps for independent flow control. The EM-CAX is also compatible with the EM-GSM gas shield for volatile solvent systems.

The EM-TMM uses a laser-based differential distance measurement principle. A laser module mounted on a precision metrology frame measures the distance to the collector surface and to the growing electrospun layer — calculating thickness from the difference. It works reliably even on highly porous structures. Variation is typically 5σ < 50 µm, and the system monitors layer build-up at one or more locations simultaneously, even at high collector speeds.

For flat membranes up to 200 × 300 mm with controllable alignment, the EM-RDC rotating drum collector is the standard choice. For tubular structures — from millimeter-scale vascular grafts to larger tissue-engineering tubes — the EM-RTC rotating target collector accepts custom mandrels and drums from Ø0.5 to 90 mm. If you need highly porous scaffolds with void-templating via ice crystals, the EM-LTE low-temperature collector achieves up to 99.8% porosity. For quick material screening, stationary EM-CXX collector plates on the EM-STD nozzle stand provide a simple, fast setup.

Yes. Every EC-CLI add-on module is designed with a plug-and-play architecture and can be added to any existing EC-CLI system at any time — no hardware modifications to the base machine are needed. Modules are controlled through the integrated touch-screen UI and, in most cases, require no additional software installation beyond optional upgrades.

The EC-CLI is the R&D backbone of VIVOLTA’s own contract development services. Processes developed on the EC-CLI can be transferred and validated on VIVOLTA’s MediSpin™ production platform in our ISO 13485–certified facility — creating a seamless path from lab-scale research to clinical and commercial manufacturing.

Yes. VIVOLTA ships the EC-CLI worldwide, including the US, Japan, and Australia. We provide on-site installation, training, and ongoing service and maintenance packages globally. A US-specific power converter kit is available for labs running 480 VAC 3-phase power.

The EC-CLI supports flat meshes, tubular structures (from sub-millimeter blood vessel mandrels to 90 mm drums), aligned fiber membranes, and complex 3D geometries. With coaxial nozzles you can produce core–shell fibers, and multi-nozzle configurations enable multi-component or high-throughput spinning.

The EC-CLI is the only electrospinning machine with fully integrated climate control as standard. Temperature and humidity are independently regulated via closed-loop sensors, eliminating the environmental variability that undermines reproducibility on other systems. Its medical electrospinning heritage — developed by the same team that built VIVOLTA’s MediSpin™ production platform — means processes developed on the EC-CLI translate directly to manufacturing scale.

An electrospinning machine uses high-voltage electric fields to draw polymer solutions or melts into ultrafine fibers with diameters ranging from nanometers to a few microns. The core components include a syringe pump, high-voltage power supply, spinneret (nozzle), and collector. Advanced systems like the EC-CLI add climate control, process automation, and modular accessories for reproducible, research-grade nanofiber production.