EC-CLI R&D Electrospinning System

The EC-CLI Electrospinning System

Precision, flexibility, and automation for advanced electrospinning applications

Welcome to the future of electrospinning research with VIVOLTA’s EC-CLI electrospinning system. Designed to meet the advanced research and development needs of premier academic institutes and universities, the EC-CLI solves the persistent need of making electrospinning more consistent and reproducible. It offers unparalleled precision, flexibility, and automation, making it the ideal choice for cutting-edge electrospinning and electrospraying applications.

Known for quality since 2008, we have manufactured and sold premier electrospinning equipment all across the globe under our previous brand name IME. As VIVOLTA, we continue to sell and service our EC-CLI systems to premier academic research institutes around the world to help propel groundbreaking research forward.

Whether you are working on tissue engineering, drug delivery, or advanced materials, the EC-CLI system is your ideal partner for cutting-edge electrospinning applications.

Key features

Climate control

Achieve consistent and reproducible results with industry-leading temperature (20 – 45°C, ±0.5°C) and humidity (10 – 80%, ±2%) control. The system stabilizes temperature within 10 to 40 minutes and humidity in less than 5 minutes.

Modular design

Customize your setup with various high voltage configurations and plug-&-play add-on modules like HEPA filters, multiple translating nozzles, real-time thickness measurement, anti-statics.

Versatility

Create a wide array of electrospun forms including flat meshes, tubes, and 3D shapes. Collector modules accommodate custom-designed targets for complex forms. Nozzle and target collector stages can be controlled and positioned independently and freely. Complex fiber architectures such as co- and coaxial spinning functionality possible.

Voltage configuration

Control your process with max positive 25kV nozzle voltage nozzle and max negative 10kV collector voltage. Built-in voltage ramp functionality for increased process stability while producing thicker scaffolds.

Scalability

The EC-CLI system is scalable from small-scale laboratory experiments to larger, more complex projects.

Process automation

Benefit from real-time monitoring, data logging, and programmable functions to enhance efficiency and reduce human error.

User-Friendly Interface

Operate with ease using the full-color touch panel and intuitive user interface.

Safety and Environmental Controls

Maintain a clean and safe working environment with integrated fume hood, door switch voltage shut-off, HEPA filters.

Compact Footprint

Save valuable lab space and reduce overhead expense with significantly less required footprint vs. comparable machines.

Best-in-class technical support and consultation

Accelerate your research by utilizing the deep experience and know-how of our technical and application science team.

Unparalleled versatility

Smart design, limitless possibilities

With its modular, flexible design and expansive features, the EC-CLI is designed to help researchers answer their most challenging questions. Augmented by a diverse array of plug-and-play add-on modules, an endless variety of fiber morphologies and form factors are achievable on a single system. The EC-CLI system’s versatility make it the backbone of VIVOLTA’s contract development services, proving its value across a wide range of applications.

PRODUCT FEATURES AND BENEFITS

Fully Integrated Climate Control

The CLI’s fully-integrated climate control technology sets it apart, giving you ultimate control of your research. While other systems rely on additional modules, VIVOLTA’s climate control unit comes standard on all EC-CLI systems, because high-quality, reproducible electrospinning requires it.

  • Independent Control: Temperature and humidity are independently controlled via digital set-points, allowing for a wide range of processing conditions with industry-leading precision.
  • Quick Settling Times: The system can stabilize temperature within 10 to 40 minutes and humidity in less than 5 minutes, ensuring minimal downtime and efficient operation.
  • Closed Sensing/Feedback Loops: Independent spinning cabinet sensors verify actual temperature and humidity values in real-time versus target setpoints, maintaining setpoint stability even over long experiments.

Modularity and Flexibility

Customize your setup and tackle your most challenging experiments with the EC-CLI system’s modular, flexible design. Near infinite process setting configurations and numerous plug-&-play add-on modules allows you to tailor the system to your specific research needs. The EC-CLI is adaptable for various scales of research, from small-scale laboratory experiments to larger or more complex projects.

  • Customizable Configurations: The EC-CLI system is highly modular, enabling users to customize the setup according to their specific research needs.
  • Versatility: On the CLI, a wide array of electrospun forms are possible including flat meshes, tubes, and 3D shapes. The rotating target collector module allows mounting of custom-designed targets for complex forms. , nozzle and target collector can be controlled and positioned independently and freely. Complex fiber architectures are also achievable thanks to co- and coaxial spinning functionality, unlocking the most challenging research aims.
  • Voltage configuration: As Standard spinning from positive (nozzle) to negative (collector) voltage to attract the fiber to the collector for higher yield, cleaner spinning and hence more reproducibility. Max. positive 25kV, voltage on collector max negative 10kV (varies depending on module) with build in voltage ramp functionality for increased process stability while producing thicker scaffolds.
  • Plug-&-Play Add-ons: a wide range of add-on modules such as HEPA filters, multiple translating nozzles, real-time thickness measurement, and anti-statics enable advanced functionality and seamlessly and easily integrate with the core system.
  • Scalability: Adaptable for various scales of research, from small-scale laboratory experiments to larger, more complex projects. Built on the same fundamental architecture as VIVOLTA’s MediSpin platform, ensuring seamless process translation from R&D to production scale.

Process Automation

Enhance efficiency and reduce human error with the EC-CLI system’s advanced process automation features. Real-time monitoring and comprehensive data logging capabilities enable precise tracking and analysis of your experiments. Programmable “teach in” functions allow you to automate processes, ensuring consistent and reliable results with minimal manual intervention.

  • Real-Time Monitoring and Data Logging: Track and analyze experiments with precision through real-time monitoring and comprehensive data logging capabilities.
  • Programmable Functions: Automate processes to enhance efficiency and reduce the potential for human error.

User-Friendly Design

Experience intuitive operation with the EC-CLI system’s full-color touch panel and user-friendly interface. Designed for ease of use, the EC-CLI system requires minimal setup time, allowing researchers to start their experiments quickly and efficiently. Whether you are new to electrospinning technology or an experienced user, the EC-CLI system’s interface simplifies the process, making it accessible to all.

  • Intuitive Operation: The full-color touch panel and intuitive user interface make the EC-CLI system easy to operate, even for users new to electrospinning technology.
  • Minimal Setup Time: Designed for quick and easy setup, allowing researchers to start their experiments without extensive preparation.

Advanced Functionality

The EC-CLI system offers advanced functionality to meet the most demanding research needs. A wide range of plug-&-play modules seamlessly integrate with the core system taking your research to the next level.

  • Gas-shielding: gaseous solvent vapor colocalized at the spinneret maintains a stable spinning environment and defect-free fibers for long experiments.
  • Anti-statics: reset the static charge buildup on the equipment during long or sequential experiments to ensure consistent results from the start to the end of the day.
  • Real-time thickness measurement: patent-protected optical thickness measurement probes mesh thickness in real-time eliminating spin-for-time process variability.
  • Multi-component systems: small mandrels for small blood vessels, larger drums for ~A4 size meshes, specialty low temperature drums for higher porosity, and parallel spoke drums for aligned fibers.

Safety and Environmental Controls

Ensuring the safety of researchers and maintaining a clean working environment are paramount with the VIVOLTA EC-CLI electrospinning system. The CLI’s safety and environmental control features ensure that your research is conducted in a safe and clean setting.

  • Safety: The system includes a protective door switch and options for different high voltage configurations to ensure safe operation.
  • Clean Environment: The EC-CLI system can be equipped with an integrated fume hood and HEPA filters to minimize volatile solvent particulate and maintain a clean and safe working environment.

High-Quality Construction and Components

Constructed with high-quality materials and durable components, the EC-CLI system ensures long-term reliability and performance.

  • Durable Build: Constructed with high-quality materials and components, ensuring long-term dependability and performance.
  • Advanced Water Treatment: Includes a 6-stage reverse osmosis (RO) water treatment system with UV light, providing high-purity water for the electrospinning process.
A super zoomed in microfiber shard
A super zoomed in microfiber shard
Diverse Applications

Tissue Engineering

Create scaffolds that mimic the extracellular matrix, providing a supportive environment for cell growth and tissue regeneration. Ideal for applications in wound healing, bone regeneration, and nerve regeneration.

Medical Devices

Enhance therapeutic effectiveness with electrospun fibers used as coatings for prefabricated structures, active ingredient additives and particles, or total device fabrication.

Drug Delivery

Develop controlled release systems for targeted and sustained drug delivery. Electrospun fibers can be loaded with particles, drugs, or other therapeutic agents, providing high surface area-to-volume ratio and tunable properties.

Advanced Textiles

Produce advanced textiles with properties like water resistance, flame retardancy, and antimicrobial activity. Applications include lightweight protective clothing, wound dressings, and high performance textiles.

Filtration

Use nanofibrous membranes for air and liquid filtration due to their small pore size and high porosity. Suitable for air filtration, water filtration, and oil-water separation.

Energy Storage

Improve the performance of batteries, supercapacitors, and fuel cells with electrospun nanofibrous materials that offer high surface area and electrical conductivity.

Cosmetics

Utilize nanofibers as carriers for active cosmetic ingredients such as vitamins, antioxidants, peptides, and plant extracts. Provide targeted treatment for anti-aging, anti-scarring, UV protection, or moisturizing.

Environmental Remediation

Employ nanofibrous materials for wastewater treatment, oil spill cleanup, and air pollution control. Effectively remove pollutants and contaminants from the environment.

Food Packaging

Create innovative packaging materials with enhanced barrier properties against oxygen, moisture, and microbes. Extend the shelf life and freshness of food products with sustainable and environmentally friendly alternatives.

technical specifications

Climate control

  • Cabin temperature range: 20 – 45 deg C, +/- 0.5 deg C
  • Cabin humidity range: 10 – 80%, +/- 2%
  • Settling times temperature: 10 min – 40 min
  • Settling times humidity: < 5 minutes
  • Water treatment: 6-stage RO water treatment system with UV light
  • Climate control: independent setpoint selection and sensor readouts via HMI

General

  • Dimensions
    • Inner spinning chamber: 624 x 474 x 530 mm (w x d x h)
    • Top unit: 700 x 500 x 1050 mm (w x d x h)
    • Climate control cabin: 1200 x 750 x 930 (w x d x h)
  • Weight: 315 kg
  • Working volume: 0.15 m3
  • Door opening: 425 x 460 mm (w x h)
  • Ventilation: Ø100 and Ø50 mm exhaust (top connection)
  • User interface: touch screen control

Electrical

  • Power rating: 380 – 420 VAC, 3 phases, 16 A, 47 – 63 Hz
  • Power consumption: 5000 VA
  • Power connection: Country specific wall plug
  • Current range: 0 – 600 μA
  • Safety system: Protective door switch shut-off

 

Custom add-on modules

The EC-CLI system features custom add-on modules for plug-and-play functionality to achieve the most demanding applications.

  • High voltage upgrades:
    Different high voltage configurations possible. Dual positive HV power supply (2x +25 kV). Increased negative power supply (-10 kV)
  • Hood:
    The system can be delivered with an integrated fume hood that is placed on the control cabinet with the spinning apparatus inside
  • HEPA
    The system can be equipped with a HEPA filter yielding a low particle count environment
  • Anti-statics
    The system can be equipped with an
    anti-statics module (EM-ASM). This module
    eliminates static electric charges that build
    up during process
  • Real-time thickness measurement
  • Gas shielding
  • Multiple nozzle stages
  • Flat and rotating collectors
  • Multi-syringe accessories
Support and training

Training Programs: VIVOLTA offers comprehensive training programs for users and distribution partners to ensure they can effectively operate and maintain the EC-CLI system. Our training covers all aspects of the system, from basic operation to advanced features.

Technical Support: Our dedicated technical support team is available to assist users with any issues or questions that may arise during the use of the EC-CLI system. We are committed to providing prompt and effective support to ensure your research runs smoothly.

Custom Process Development: VIVOLTA scientists are ready to create custom protocols to achieve the most challenging application requirements more efficiently. Our expert consultation services provide tips and tricks based on decades of combined electrospinning experience and know-how.

A super zoomed in microfiber shard
A super zoomed in microfiber shard
Case Studies & Testimonials

Case Studies

Explore our case studies showcasing successful implementations of the EC-CLI system in various research projects. Learn how leading academic institutes have leveraged the EC-CLI system to achieve groundbreaking results in their fields.

Testimonials

Hear from our satisfied customers about their experiences with the EC-CLI system. Discover how the EC-CLI system has transformed their research and development processes, providing them with the precision, flexibility, and automation they need.

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